Continuous Flow <i>Z</i> ?Stereoselective Olefin Metathesis: Development and Applications in the Synthesis of Pheromones and Macrocyclic Odorant Molecules**

The first continuous flow Z-selective olefin metathesis process is reported. Key to realizing this was the adequate choice of stereoselective catalysts combined with design an appropriate reactor setup. designed permits various self-, cross- and macro-ring-closing-metathesis reactions, delivering products in high selectivity short residence times. This technique exemplified by direct application preparation a range pheromones macrocyclic odorant molecules culminates telescoped cross-metathesis/ Dieckmann cyclisation sequence access (Z)-Civetone, incorporating serial array continually stirred tank reactors.